February 16, 2012

Changing Meds Makes for Difficult Days

My patterns of depression are so familiar now, I may as well copy and paste my last blog post into this one.


Major Depression struck again a couple weeks ago. And it was pure hell. I missed one day's work and struggled like crazy to make myself keep moving for several days afterwards.

My doctor and I decided we needed to be aggressive in trying to stop it, so he changed my meds. I'm now taking Effexor along with Abilify.

The change from Cymbalta to Effexor proved to be a cautionary tale. I had been taking 60 mg of Cymbalta, which I had some success with after a mental health meltdown last summer. To transition to the new drug (Effexor), I was instructed to drop down to 30 mg of Cymbalta for three days before starting out on a small dose of Effexor. 


Only I didn't do that. My Cymbalta pills weren't the kind you can split in half, and I never got new 30 mg pills for the three-day transition period. So I just stopped the Cymbalta cold turkey. I won't do that again.

Wrenching anxiety, stomach aches and feelings of utter hopelessness soon came. 
It was a brutal stretch, probably ranking in my all-time Top 10 list of major depressive episodes.

I'm not exactly copacetic now, but I'm much better. The suicidal ideations that haunted me have subsided. I feel more hopeful than I did even a week ago.

I've now ramped up the dosage of Effexor as the doctor prescribed, and I think it's beginning to pay off.

Those who suffer from depression can relate to the difficulty of changing meds. We often get worse before we get better. And that's really frustrating.

I haven't figured this thing out yet, but I'm trying to remain optimistic about the future. It generally takes 2 to 4 weeks for a new antidepressant to really help. My doctor says it takes much longer—maybe six months—to get the full payoff.

So I wait patiently, doing the other things I know help (exercise, eating less junk, etc.)

I only wish Punxsutawney Phil hadn't seen his shadow. I hate darkness and winter and am ready for it to end.

My guess is many of my fellow depression sufferers feel the same way.

P.S. I hope the few of you who know me understand the difference between the sort of fleeting suicidal ideations I occasionally have and the more serious suicidal thoughts that others experience that involve plans, etc. I've never gotten that far before and don't plan to. I have too much to live for and a burning to desire to defeat depression. I share the brutal realities of depression only so others who feel them like I do don't feel so alone.

14 comments:

  1. I'm sorry you've been feeling so poorly. I understand. I also understand the frustration of trying new meds. I've taken Zoloft for more than a decade -barely helps anymore, but not taking it is just bad. I tried adding an antidepressant this past summer. Months of increasing doses to no avail until finally it just made me worse. Now, I'm just back to Zoloft alone. My doctors were wanting me to try Abilify, but I don't want to try anything new. It's definitely frustrating, but for lots of people it pays off. I hope you start feeling well soon. Not too much longer till Spring. Take care. ~rl

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  2. rl,
    Thanks for stopping by. It's great to hear from people who can truly relate.

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  3. Most of last year I seemed to be either coming off a med or starting a new one. I look back at some of the attempts and in hindesight they were making me worse (Lexepro was so not right for me). I have currently been on Parnate for many months. I have to take 2 night meds to counteract the not bring able to sleep side effect of the Parnate though. I'm always asked if I think the combination is working but I don't really know. Is it the other changes I have made in my life that are helping or is it the medication?
    I wish you all the best during this time.

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  4. J-M,
    I wish you the best as well. I can certainly relate to your struggles.

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  5. Hey Bro, nice blog.... I have suffered chronic, recurrent major depression for the last 20 years....about 12-12-1994 I attempted suicide.

    am on 300 mg of zoloft daily.....has been working for me for the last 6 months....

    We go on....as we do glad to hear you have at least occassional ups.

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  6. Wonderful post. You just need to be optimistic in handling all of these things. I know it would be hard for you at first but I'm pretty sure that you can cope up with it in the future.

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  7. I somehow understand what you feel but I didn't experienced on what happened to you. I know you can overcome it, just continue to strive for self satisfaction, be positive in all ways. Create a goal for yourself.

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  10. You haven't been on here for a long time! Have you gone to another blogging site or have you been bloody crook? I hope you're OK. I've had great results backing up Effexor with prescribed supplements from my very conventional (or used to be) shrink. Pure fish oils (liquid form) daily, Vitamin D oil monthly (100 000 units) and lots of anti oxidant foods like berries daily. Your blog is a beauty- we want more!

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  11. Good post. Value the honesty. Love the courage found in your blog. I would expect helpful to many. Thank you! I started a blog this year hoping to offer bits of hope, thoughts and ideas that could make a difference.
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  12. Jack, I share lots of your feelings. I wish we knew the other suffered from this debilitating disease before now, i think that we could have talked and shared and helped each other. I have tried every antidepressant out yhere & now for years I have been on a large dose of Effexor & Topamax. I have had many thoughts of suicide.......

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  13. Liz,
    I am really sorry to hear this but glad you shared. Would love to talk sometime when I get back. I've been on a large dose of effexor as well and it helped me for a long time. I only wish it were permanent. If we have suicide thoughts, we need to share them with our family or at least our doctor or therapist. I made the mistake of not sharing mine and it nearly cost me everything. My faith in people has been restored since "going public" with my illness....I can feel the power of prayer. I will be praying for you.

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  14. Kay,
    I'm back...thanks for asking and thanks for your awesome tips.
    Jack

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